The AOC3 Polyclonal Antibody (CAB2001) is a valuable tool for researchers studying AOC3, a key enzyme involved in the regulation of oxidative stress and inflammation. This antibody, produced in rabbits, demonstrates high specificity and sensitivity for human samples, making it an ideal choice for Western blot applications.AOC3, also known as amine oxidase copper-containing 3, plays a crucial role in the metabolism of biogenic amines and has been implicated in various pathophysiological processes, including cardiovascular disease and diabetes.
By targeting AOC3 with this polyclonal antibody, researchers can effectively detect and analyze the enzyme in different cell types, providing valuable insights for studies in metabolism, cardiovascular biology, and oxidative stress-related diseases.The AOC3 Polyclonal Antibody (CAB2001) is a reliable tool for investigating the function and regulation of AOC3 in various biological contexts, offering new possibilities for therapeutic interventions targeting this enzyme in disease settings.
Product Name:
AOC3 Rabbit Polyclonal Antibody
SKU:
CAB2001
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 27-190 of human AOC3 (NP_003725.1).
Cell membrane, Single-pass type II membrane protein.
Calculated MW:
85kDa
Observed MW:
101kDa
This gene encodes a member of the semicarbazide-sensitive amine oxidase family. Copper amine oxidases catalyze the oxidative conversion of amines to aldehydes in the presence of copper and quinone cofactor. The encoded protein is localized to the cell surface, has adhesive properties as well as monoamine oxidase activity, and may be involved in leukocyte trafficking. Alterations in levels of the encoded protein may be associated with many diseases, including diabetes mellitus. A pseudogene of this gene has been described and is located approximately 9-kb downstream on the same chromosome. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
8639
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Mouse fat, using AOC3 antibody (CAB2001) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
