The AOC1 Polyclonal Antibody (CAB6249) is a valuable tool for researchers studying AOC1, a cell surface protein involved in immune regulation and inflammation. This antibody, produced in rabbits, has high reactivity with human samples and is validated for use in Western blot applications. By binding to the AOC1 protein, this antibody allows for the detection and analysis of AOC1 in various cell types, making it ideal for research in immunology and cancer biology.
AOC1, also known as amine oxidase, plays a crucial role in immune homeostasis by regulating the inflammatory response and allergic reactions. Its involvement in immune modulation makes it a promising target for studying diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions. Understanding the function of AOC1 is essential for developing therapies that can manipulate immune responses in these disease settings.
Product Name:
AOC1 Rabbit Polyclonal Antibody
SKU:
CAB6249
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-300 of human AOC1 (NP_001082.2).
This gene encodes a metal-binding membrane glycoprotein that oxidatively deaminates putrescine, histamine, and related compounds. The encoded protein is inhibited by amiloride, a diuretic that acts by closing epithelial sodium ion channels. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
26
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using AOC1 antibody (CAB6249) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
