Annexin A4/Annexin IV Rabbit Polyclonal Antibody (CAB13466)
The ANXA4 Polyclonal Antibody (CAB13466) is a powerful tool for researchers studying ANXA4, a protein involved in various cellular processes such as cell signaling, proliferation, and apoptosis. This antibody, generated in rabbits, shows high specificity and sensitivity towards human samples and is validated for use in Western blot applications.ANXA4, also known as annexin A4, is a member of the annexin family of proteins that play a role in calcium-dependent membrane events. It is implicated in cancer progression, cell migration, and invasion, making it a target of interest in cancer research.
By targeting ANXA4 with this antibody, researchers can investigate its function and potential therapeutic implications in cancer and other diseases.Overall, the ANXA4 Polyclonal Antibody (CAB13466) offers a valuable tool for researchers looking to explore the role of ANXA4 in cellular processes and diseases, providing insights that could lead to new therapeutic strategies.
Product Name:
Annexin A4/Annexin IV Rabbit Polyclonal Antibody
SKU:
CAB13466
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 112-321 of human Annexin A4/Annexin IV (NP_001144.1).
ANX4; P32.5; PIG28; PP4-X; ZAP36; PAP-II; HEL-S-274; Annexin A4/Annexin IV
Positive Sample:
Mouse liver,Mouse kidney
Conjugate:
Unconjugated
Cellular Localization:
cell surface, cytoplasm, cytoplasmic vesicle, extracellular exosome, nuclear membrane, nucleus, perinuclear region of cytoplasm, plasma membrane
Calculated MW:
36kDa
Observed MW:
36kDa
Annexin IV (ANX4) belongs to the annexin family of calcium-dependent phospholipid binding proteins. Although their functions are still not clearly defined, several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. ANX4 has 45 to 59% identity with other members of its family and shares a similar size and exon-intron organization. Isolated from human placenta, ANX4 encodes a protein that has possible interactions with ATP, and has in vitro anticoagulant activity and also inhibits phospholipase A2 activity. ANX4 is almost exclusively expressed in epithelial cells. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
307
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Annexin A4/Annexin IV antibody (CAB13466) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
