null

ANXA1 Monoclonal Antibody [PAT2G5AT] (CPAB0625)

SKU:
CPAB0625
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Universal
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT2G5AT
Applications:
WB
ELISA
€149

Description

system_update_alt Datasheet

ANXA1 Monoclonal Antibody [PAT2G5AT] (CPAB0625)

The ANXA1 Polyclonal Antibody (CPAB0625) is a valuable tool for researchers studying ANXA1, a protein known for its role in inflammation and immune regulation. This antibody, produced in rabbits, is highly specific to human ANXA1 samples and is validated for use in various applications, including Western blot analysis.ANXA1, also known as Annexin A1, is a key player in the regulation of inflammatory responses and has been implicated in various diseases, including cancer and autoimmune disorders.

By targeting ANXA1, researchers can gain insights into the mechanisms underlying these conditions and potentially develop new therapeutic approaches.With its high reactivity and specificity, the ANXA1 Polyclonal Antibody is an essential resource for studies in immunology, cancer research, and inflammation. Its ability to detect and quantify ANXA1 protein levels in different cell types makes it a versatile tool for investigating the role of ANXA1 in various biological processes.

Product Name:ANXA1 Antibody
Product Sku:CPAB0625
Size:5μg
Host Species:Mouse
Immunogen:Anti-human ANXA1 mAb, clone PAT2G5AT, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human ANXA1 protein 1-346 amino acids purified from Ecoli.
Clone:PAT2G5AT
Reactivity:Other bodies
Applications:Western Blot, ELISA
Purification Method:ANXA1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2a
Background:ANXA1 is part of the family of Ca(2+)-dependent phospholipid binding proteins which have a Mw between 35kDa-40kDa and are situated on the cytosolic face of the plasma membrane. ANXA1 protein has a Mw of 40kDa, with phospholipase A2 inhibitory activity to bind from two to four calcium ions with high affinity. Since phospholipase A2 is necessary for the biosynthesis of the potent mediators of inflammation, prostaglandins and leukotrienes, ANXA1 might have potential anti-inflammatory activity. ANXA1 promotes membrane fusion and iplays a role in exocytosis. The recognition of ANXA1 protein by immunocytochemical leads a simple, highly sensitive and specific assay for diagnosis of hairy cell leukemia.
Synonyms:ANX1, LPC1, ANXA1, Lipocortin I, Calpactin II, Chrombindin-9, p35, Annexin-1, Phospholipase A2 inhibitory protein, Annexin I, Annexin A1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

Related Products