The ANTXR2 Polyclonal Antibody (CAB6526) is a valuable tool for researchers studying ANTXR2, a cell surface receptor involved in various cellular processes, including cell adhesion and migration. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the ANTXR2 protein, this antibody enables the detection and analysis of ANTXR2 in various cell types, making it an excellent choice for studies in cell biology and cancer research.
ANTXR2, also known as Anthrax toxin receptor 2, is an important protein that plays a role in cellular processes such as extracellular matrix adhesion and angiogenesis. Dysregulation of ANTXR2 has been linked to various diseases, including cancer and fibrosis, highlighting its significance as a potential therapeutic target. Research into the function of ANTXR2 may provide insights into disease mechanisms and help in the development of novel treatments targeting this receptor.
Product Name:
ANTXR2 Rabbit Polyclonal Antibody
SKU:
CAB6526
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 34-300 of human ANTXR2 (NP_001139266.1).
Cell membrane, Endoplasmic reticulum membrane, Secreted, Single-pass type I membrane protein, Single-pass type I membrane protein.
Calculated MW:
54kDa
Observed MW:
54kDa
This gene encodes a receptor for anthrax toxin. The protein binds to collagen IV and laminin, suggesting that it may be involved in extracellular matrix adhesion. Mutations in this gene cause juvenile hyaline fibromatosis and infantile systemic hyalinosis. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
118429
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using ANTXR2 Rabbit pAb (CAB6526) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
