The ZNF259 Monoclonal Antibody (CAB1487) is a valuable tool for researchers studying the ZNF259 protein, which plays a role in gene regulation and cellular processes. This antibody, developed using advanced technology, specifically targets ZNF259 and is highly reactive in human samples. With validation for use in Western blot applications, this antibody enables the detection and analysis of ZNF259 in various cell types.ZNF259 is a transcription factor that regulates gene expression, making it essential for understanding cellular pathways and disease mechanisms.
Research on ZNF259 has implications in cancer biology, neurodegenerative disorders, and developmental biology. By targeting ZNF259, researchers can gain crucial insights into gene regulation and cellular functions, leading to advancements in therapeutic strategies and disease treatments.
Product Name:
ZNF259 Rabbit Monoclonal Antibody
SKU:
CAB1487
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 360-459 of human ZNF259 (O75312).
The protein encoded by this gene is found in the cytoplasm of quiescent cells but translocates to the nucleolus in proliferating cells. The encoded protein interacts with survival motor neuron protein (SMN1) to enhance pre-mRNA splicing and to induce neuronal differentiation and axonal growth. Defects in this gene or the SMN1 gene can cause spinal muscular atrophy. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8882
Clone Number:
ARC2563
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse brain, using ZNF259 Rabbit mAb (CAB1487) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
