The YAP1 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0318) is a cutting-edge tool for researchers studying the YAP1 protein, a key regulator of cell proliferation and apoptosis. This antibody, created using advanced chimeric recombinant technology, exhibits high specificity and sensitivity for detecting YAP1 in human samples.YAP1, a transcriptional co-activator, is involved in the Hippo signaling pathway and plays a crucial role in controlling organ size, tissue regeneration, and tumorigenesis. Dysregulation of YAP1 has been implicated in various cancers, making it a promising target for cancer therapy research.
The YAP1 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0318) enables precise detection and analysis of YAP1 expression in different cell types and tissues, providing valuable insights into its functions and potential therapeutic applications. Its reliability and versatility make it an essential tool for immunology and cancer research projects aiming to unravel the complex mechanisms governed by the YAP1 protein.
SKU:
HDAB0318
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC495
Synonyms:
COB1, YAP, YAP2, YAP65, YKI
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a downstream nuclear effector of the Hippo signaling pathway which is involved in development, growth, repair, and homeostasis. This gene is known to play a role in the development and progression of multiple cancers as a transcriptional regulator of this signaling pathway and may function as a potential target for cancer treatment. Alternative splicing results in multiple transcript variants encoding different isoforms.
