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XPD/ERCC2 Rabbit Monoclonal Antibody (CAB19241)

SKU:
CAB19241
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
ERCC2
COFS2
EM9
TFIIH
TTD
TTD1
XPD
ERCC excision repair 2
TFIIH core complex helicase subunit
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:XPD/ERCC2 Rabbit Monoclonal Antibody
SKU:CAB19241
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 600-700 of human XPD/ERCC2 (P18074).
Sequence:ARGK VSEG IDFV HHYG RAVI MFGV PYVY TQSR ILKA RLEY LRDQ FQIR ENDF LTFD AMRH AAQC VGRA IRGK TDYG LMVF ADKR FARG DKRG KLPR WIQE H
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:EM9; TTD; XPD; TTD1; COFS2; TFIIH; XPD/ERCC2
Positive Sample:HeLa,293T,A-549
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Nucleus, cytoskeleton, spindle.
Calculated MW:87kDa
Observed MW:80kDa

The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:2068
Clone Number:ARC2401
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using XPD/ERCC2 Rabbit mAb (CAB19241) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.

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