XPD/ERCC2 Rabbit Monoclonal Antibody (CAB19241)
- SKU:
- CAB19241
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ERCC2
- COFS2
- EM9
- TFIIH
- TTD
- TTD1
- XPD
- ERCC excision repair 2
- TFIIH core complex helicase subunit
Frequently bought together:
Description
Product Name: | XPD/ERCC2 Rabbit Monoclonal Antibody |
SKU: | CAB19241 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 600-700 of human XPD/ERCC2 (P18074). |
Sequence: | ARGK VSEG IDFV HHYG RAVI MFGV PYVY TQSR ILKA RLEY LRDQ FQIR ENDF LTFD AMRH AAQC VGRA IRGK TDYG LMVF ADKR FARG DKRG KLPR WIQE H |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 |
Synonyms: | EM9; TTD; XPD; TTD1; COFS2; TFIIH; XPD/ERCC2 |
Positive Sample: | HeLa,293T,A-549 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, cytoskeleton, spindle. |
Calculated MW: | 87kDa |
Observed MW: | 80kDa |
The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 2068 |
Clone Number: | ARC2401 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |