The Anti-Wnt2b Antibody (CAB19554) is a polyclonal antibody specifically designed for research involving Wnt2b, a key signaling protein involved in various cellular processes including embryonic development, tissue regeneration, and tumorigenesis. This antibody, produced through rabbit immunization, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the Wnt2b protein, researchers can detect and analyze its expression in different cell types, making it an essential tool for studies in developmental biology, stem cell research, and cancer biology.
Wnt2b is a member of the Wnt family of secreted glycoproteins that play crucial roles in cell proliferation, differentiation, and migration. Dysregulation of Wnt signaling pathways, including Wnt2b, has been associated with various diseases such as cancer, developmental disorders, and degenerative diseases. By studying the expression and function of Wnt2b using this antibody, researchers can gain insights into the mechanisms underlying these diseases and potentially identify new therapeutic targets for intervention.
Product Name:
WNT2B Rabbit Monoclonal Antibody
SKU:
CAB19554
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 200-300 of human WNT2B (Q93097).
This gene encodes a member of the wingless-type MMTV integration site (WNT) family of highly conserved, secreted signaling factors. WNT family members function in a variety of developmental processes including regulation of cell growth and differentiation and are characterized by a WNT-core domain. This gene may play a role in human development as well as carcinogenesis. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
7482
Clone Number:
ARC2172
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using WNT2B Rabbit mAb (CAB19554) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
