The WDR46 Polyclonal Antibody (CAB20466) is designed for research involving WDR46, a protein involved in cellular processes and gene expression regulation. The antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications, including Western blot and immunofluorescence. It specifically binds to the WDR46 protein, enabling detection and analysis in different cell types and tissues, making it a valuable tool for studies in molecular biology and cancer research.WDR46, also known as WD repeat-containing protein 46, plays a crucial role in chromatin remodeling and transcriptional regulation, making it a key player in gene expression control.
Its involvement in these processes makes it a promising target for research into diseases like cancer, where dysregulation of gene expression is commonly observed. Understanding the function of WDR46 is essential for uncovering its potential role in disease development and progression, as well as identifying new therapeutic targets.
Product Name:
WDR46 Rabbit Polyclonal Antibody
SKU:
CAB20466
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 421-610 of human WDR46 (NP_005443.3).
Enables RNA binding activity. Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be located in nucleoplasm. Predicted to be part of small-subunit processome. Predicted to be active in nucleolus.
Purification Method:
Affinity purification
Gene ID:
9277
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma using WDR46 Rabbit pAb (CAB20466) at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.