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WAVE2/WASF2 Rabbit Monoclonal Antibody (CAB19601)

SKU:
CAB19601
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
IMD2
SCAR2
WASF4
WAVE2
dJ393P12.2
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:WAVE2/WASF2 Rabbit Monoclonal Antibody
SKU:CAB19601
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 399-498 of human WAVE2/WASF2 (Q9Y6W5).
Sequence:PPGP PPPP FTGA DGQP AIPP PLSD TTKP KSSL PAVS DARS DLLS AIRQ GFQL RRVE EQRE QEKR DVVG NDVA TILS RRIA VEYS DSED DSSE FDED DWSD
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:50 - 1:200
Synonyms:IMD2; SCAR2; WASF4; WAVE2; dJ393P12.2; WAVE2/WASF2
Positive Sample:A549,K-562,Mouse testis,Mouse thymus
Conjugate:Unconjugated
Cellular Localization:Actin cytoskeleton, Basolateral plasma membrane, Cell-cell junction, Cytosol, early endosome, Extracellular exosome, SCAR complex
Calculated MW:54kDa
Observed MW:80kDa

This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene.

Purification Method:Affinity purification
Gene ID:10163
Clone Number:ARC2191
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using WAVE2/WAVE2/WASF2 Rabbit mAb (CAB19601) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.

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