Similarly, the WAPL Polyclonal Antibody (CAB5923) is a valuable tool for researchers studying the WAPL protein, which is involved in chromosomal segregation and condensation during cell division. This antibody, produced in rabbits, is specifically reactive with human WAPL samples and has been validated for use in applications such as Western blotting.The WAPL protein is crucial for ensuring the accurate distribution of genetic material during cell division, making it a key player in maintaining genomic stability. Dysregulation of WAPL function has been implicated in diseases such as cancer, where abnormal cell division can lead to uncontrolled growth and tumor formation.
By understanding the role of WAPL in chromosomal dynamics, researchers can uncover potential therapeutic targets for cancer treatment and other genetic disorders.Overall, the WAPL Polyclonal Antibody (CAB5923) is a reliable tool for researchers investigating the role of the WAPL protein in cellular processes, offering valuable insights into chromosomal dynamics and potential implications for disease pathology.
Product Name:
WAPL Rabbit Monoclonal Antibody
SKU:
CAB5923
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human WAPL (Q7Z5K2).
Involved in several processes, including negative regulation of DNA replication; negative regulation of chromatin binding activity; and regulation of sister chromatid cohesion. Located in several cellular components, including Golgi apparatus; intercellular bridge; and microtubule cytoskeleton.
Purification Method:
Affinity purification
Gene ID:
23063
Clone Number:
ARC2088
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using WAPL Rabbit mAb (CAB5923) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
