The Anti-VWF Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0257) is a cutting-edge tool for researchers studying von Willebrand Factor (VWF), a key protein involved in blood clotting and platelet function. This monoclonal antibody, developed using advanced recombinant technology, offers high specificity and sensitivity in detecting VWF in various sample types.Raised in rabbits, this antibody is optimized for use in a variety of applications, including immunohistochemistry and flow cytometry. Its chimeric nature allows for enhanced stability and affinity, ensuring reliable and reproducible results in experimental settings.VWF is essential for hemostasis, and abnormalities in its function are associated with bleeding disorders such as von Willebrand disease.
By targeting VWF with this monoclonal antibody, researchers can further unravel the intricate mechanisms underlying blood coagulation and potentially develop targeted therapies for VWF-related disorders.Overall, the Anti-VWF Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0257) is a valuable tool for investigators delving into the complexities of VWF biology and its implications in health and disease. Its high-quality performance and versatility make it an indispensable asset in research focusing on thrombosis, hemostasis, and cardiovascular conditions.
SKU:
HDAB0257
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC389
Synonyms:
F8VWF; VWD
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22.
