The anti-vWF Antibody (CAB13523) offered by Assay Genie is a highly specific and reliable tool for research involving von Willebrand Factor (vWF), a key protein involved in blood clotting and hemostasis. This polyclonal antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in applications such as Western blotting.vWF is essential for platelet adhesion and aggregation at sites of vascular injury, making it a crucial component of the coagulation cascade. Dysregulation of vWF has been implicated in various bleeding disorders and thrombotic conditions, highlighting the importance of studying its function in both health and disease contexts.
The anti-vWF Antibody (CAB13523) enables accurate detection and analysis of vWF in a variety of cell types, making it ideal for research in hematology, vascular biology, and cardiovascular diseases. By understanding the role of vWF in blood clot formation and vascular health, researchers can gain insights that may lead to the development of novel therapies for clotting disorders, cardiovascular diseases, and other conditions related to hemostasis.
Product Name:
VWF Rabbit Monoclonal Antibody
SKU:
CAB13523
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1150-1300 of human von Willebrand factor (VWF) (P04275).
This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22.
Purification Method:
Affinity purification
Gene ID:
7450
Clone Number:
ARC0716
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse liver, using von Willebrand factor (VWF) Rabbit mAb (CAB13523) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
