The VSIG4 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0226) is a cutting-edge tool for researchers studying the VSIG4 protein, a critical immune checkpoint regulator. This antibody, developed using innovative chimeric recombinant technology, offers high specificity and sensitivity for detecting VSIG4 in human samples. Validated for use in various applications, including Western blotting, this antibody enables precise analysis of VSIG4 expression in different cell types.VSIG4, also known as V-set and immunoglobulin domain-containing 4, is a key player in immune regulation, particularly in controlling immune responses and maintaining immune tolerance.
Its role in modulating immune function makes it a promising target for research in fields such as immunology and oncology. By studying the function of VSIG4, researchers can gain insights into immune dysregulation in diseases like cancer, autoimmune disorders, and inflammatory conditions, paving the way for the development of novel therapeutic strategies.
SKU:
HDAB0226
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC268
Synonyms:
CRIg; Z39IG
Applications:
Flow Cyt
Recommended Dilution:
Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a v-set and immunoglobulin-domain containing protein that is structurally related to the B7 family of immune regulatory proteins. The encoded protein may be a negative regulator of T-cell responses. This protein is also a receptor for the complement component 3 fragments C3b and iC3b. Alternate splicing results in multiple transcript variants.
