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VPS24 Rabbit Monoclonal Antibody (CAB0941)

SKU:
CAB0941
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
CGI-149
NEDF
VPS24
Research Area:
Cell Death
€139 - €419
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:VPS24 Rabbit Monoclonal Antibody
SKU:CAB0941
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:Recombinant fusion protein containing a sequence corresponding to amino acids 65-220 of human VPS24 (Q9Y3E7).
Sequence:KEMI RSRK AVSK LYAS KAHM NSVL MGMK NQLA VLRV AGSL QKST EVMK AMQS LVKI PEIQ ATMR ELSK EMMK AGII EEML EDTF ESMD DQEE MEEE AEME IDRI LFEI TAGA LGKA PSKV TDAL PEPE PPGA MAAS EDEE EEEE ALEA MQSR LATL
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:NEDF; VPS24; CGI-149
Positive Sample:293T,A549,SH-SY5Y,Mouse brain,Rat brain
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Endosome, Late endosome membrane, Lipid-anchor, Membrane, cytosol.
Calculated MW:25kDa
Observed MW:29kDa

This gene encodes a protein that sorts transmembrane proteins into lysosomes/vacuoles via the multivesicular body (MVB) pathway. This protein, along with other soluble coiled-coil containing proteins, forms part of the ESCRT-III protein complex that binds to the endosomal membrane and recruits additional cofactors for protein sorting into the MVB. This protein may also co-immunoprecipitate with a member of the IFG-binding protein superfamily. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the upstream ring finger protein 103 (RNF103) gene.

Purification Method:Affinity purification
Gene ID:51652
Clone Number:ARC1849
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various cell lines, using VPS24 Rabbit mAb (CAB0941) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.

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