von Willebrand factor (VWF) Monoclonal Antibody (CAB21054)
The Anti-Von Willebrand Factor (VWF) Antibody (CAB21054) is a valuable tool for researchers studying Von Willebrand Factor, a key protein involved in blood clotting and platelet adhesion. This polyclonal antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for various research applications.Von Willebrand Factor is essential for the normal functioning of the hemostatic system, playing a crucial role in the formation of blood clots and preventing excessive bleeding. Dysregulation of VWF has been implicated in various bleeding disorders, making it a target of interest for researchers in the fields of hematology and vascular biology.
The Anti-VWF Antibody (CAB21054) can be used in a variety of experimental techniques, including Western blotting, immunohistochemistry, and flow cytometry, to detect and analyze VWF expression in different cell types and tissues. Its high specificity and sensitivity make it a valuable tool for understanding the role of VWF in physiological and pathological conditions, paving the way for the development of targeted therapies for bleeding disorders and cardiovascular diseases.
Product Name:
von Willebrand factor (VWF) Monoclonal Antibody
SKU:
CAB21054
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2645-2813 of human von Willebrand factor (VWF) (NP_000543.3).
This gene encodes a glycoprotein involved in hemostasis. The encoded preproprotein is proteolytically processed following assembly into large multimeric complexes. These complexes function in the adhesion of platelets to sites of vascular injury and the transport of various proteins in the blood. Mutations in this gene result in von Willebrand disease, an inherited bleeding disorder. An unprocessed pseudogene has been found on chromosome 22.
Purification Method:
Affinity purification
Gene ID:
7450
Clone Number:
ARC52173
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human colon carcinoma using von Willebrand factor (VWF) Rabbit mAb (CAB21054) at dilution of 1:800 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
