VAV3 Rabbit Monoclonal Antibody (CAB9583)
- SKU:
- CAB9583
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | VAV3 Rabbit Monoclonal Antibody |
SKU: | CAB9583 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 700-800 of human VAV3 (Q9UKW4). |
Sequence: | TKES GEYA ISIK YNNE AKHI KILT RDGF FHIA ENRK FKSL MELV EYYK HHSL KEGF RTLD TTLQ FPYK EPEH SAGQ RGNR AGNS LLSP KVLG IAIA RYDF C |
Tested Applications: | WB IHC-P ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IHC-P,1:50 - 1:200 |
Positive Sample: | Jurkat,Mouse brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Cytosol, Plasma membrane |
Calculated MW: | 98kDa |
Observed MW: | 98kDa |
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.
Purification Method: | Affinity purification |
Gene ID: | 10451 |
Clone Number: | ARC1647 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |