The Vav2 Polyclonal Antibody (CAB3548) is a valuable tool for studying the Vav2 protein, a key regulator of cell signaling pathways involved in various cellular processes. This antibody, produced in rabbits, exhibits high specificity and reactivity towards human samples, making it ideal for use in Western blot applications.Vav2 is a member of the Vav family of guanine nucleotide exchange factors (GEFs) that play a crucial role in the transduction of extracellular signals into the cell, ultimately influencing processes such as cell proliferation, differentiation, and migration.
Aberrant activation or expression of Vav2 has been implicated in various diseases, including cancer and immune disorders, highlighting its importance as a potential therapeutic target.By targeting the Vav2 protein, researchers can gain insights into its function and role in disease pathogenesis, paving the way for the development of novel therapeutic strategies. The Vav2 Polyclonal Antibody (CAB3548) is a valuable tool for further elucidating the intricate mechanisms governed by Vav2 in both physiological and pathological contexts.
Product Name:
VAV2 Rabbit Monoclonal Antibody
SKU:
CAB3548
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human VAV2 (P52735).
Sequence:
FDVR DFGK VISA VSRL SLHS IAQN KGIR PFPS EETT ENDD DVYR SLEE LADE HDLG EDIY DCVP CEDG GDDI YEDI IKVE VQQP MIRY MQKM GMTE DDKR N
VAV2 is the second member of the VAV guanine nucleotide exchange factor family of oncogenes. Unlike VAV1, which is expressed exclusively in hematopoietic cells, VAV2 transcripts were found in most tissues. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
7410
Clone Number:
ARC2041
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using VAV2 Rabbit mAb (CAB3548) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
