The VAMP8 Polyclonal Antibody (CAB4728) is a valuable tool for researchers studying VAMP8, a protein involved in membrane fusion processes essential for intracellular vesicle trafficking. This antibody is produced in rabbits and exhibits high reactivity with human samples, making it suitable for use in Western blot applications. By binding to the VAMP8 protein, this antibody enables the detection and analysis of VAMP8 in various cell types, facilitating investigations in cell biology and neurobiology.VAMP8, also known as vesicle-associated membrane protein 8, plays a crucial role in regulating the secretion of various molecules, including neurotransmitters and immune mediators.
Its involvement in intracellular transport and exocytosis processes makes it a key player in diverse physiological functions, such as synaptic transmission and immune cell activation. Research on VAMP8 is essential for understanding these processes and their implications in health and disease, particularly in neurological disorders and immune-related conditions.
Product Name:
VAMP8 Rabbit Monoclonal Antibody
SKU:
CAB4728
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human VAMP8 (NP_003752.2).
cytoplasm, cytosol, early endosome, extracellular exosome, perinuclear region of cytoplasm, plasma membrane, recycling endosome, SNARE complex
Calculated MW:
11kDa
Observed MW:
15kDa
This gene encodes an integral membrane protein that belongs to the synaptobrevin/vesicle-associated membrane protein subfamily of soluble N-ethylmaleimide-sensitive factor attachment protein receptors (SNAREs). The encoded protein is involved in the fusion of synaptic vesicles with the presynaptic membrane.
Purification Method:
Affinity purification
Gene ID:
8673
Clone Number:
ARC1108
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using VAMP8 Rabbit mAb (CAB4728) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
