The VAMP7 Polyclonal Antibody (CAB18698) is a valuable tool for researchers studying VAMP7, a member of the vesicle-associated membrane protein (VAMP) family involved in membrane fusion events within cells. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.VAMP7 is known to play a crucial role in regulating intracellular membrane trafficking, particularly within the endosomal-lysosomal pathway. Dysfunction of VAMP7 has been implicated in various diseases, including neurodegenerative disorders and infectious diseases.
By targeting VAMP7 with this antibody, researchers can gain insights into its function and potential implications for disease pathology.This antibody is a valuable tool for studying intracellular membrane dynamics and may have implications for therapeutic development in diseases where VAMP7 dysregulation is a contributing factor. Its versatility in detecting VAMP7 in different cell types makes it suitable for a wide range of research applications in cell biology and molecular biology.
Product Name:
VAMP7 Rabbit Polyclonal Antibody
SKU:
CAB18698
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2-121 of human VAMP7 (P51809).
This gene encodes a transmembrane protein that is a member of the soluble N-ethylmaleimide-sensitive factor attachment protein receptor (SNARE) family. The encoded protein localizes to late endosomes and lysosomes and is involved in the fusion of transport vesicles to their target membranes. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
6845
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using VAMP7 Rabbit pAb (CAB18698) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 60s.
