The USP39 Polyclonal Antibody (CAB1393) is an essential tool for researchers studying USP39, a key protein involved in RNA splicing and DNA repair processes. This antibody, produced in rabbits, exhibits strong reactivity towards human samples and is validated for use in Western blot applications. By specifically binding to the USP39 protein, this antibody enables precise detection and analysis in a variety of cell types, making it an invaluable asset for investigations in molecular biology and cancer research.
USP39, also known as a ubiquitin-specific protease, plays a crucial role in maintaining genomic stability and ensuring proper gene expression through its involvement in RNA splicing mechanisms. Its significance in cellular processes makes USP39 a promising target for research into cancer development, genetic disorders, and RNA-related diseases. Understanding the functions of USP39 is essential for the development of targeted therapies and diagnostic tools aimed at addressing these pathological conditions.
Product Name:
USP39 Rabbit Monoclonal Antibody
SKU:
CAB1393
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human USP39 (Q53GS9).
Predicted to enable thiol-dependent deubiquitinase and zinc ion binding activity. Involved in spliceosomal complex assembly. Located in nucleoplasm. Part of U4/U6 x U5 tri-snRNP complex.
Purification Method:
Affinity purification
Gene ID:
10713
Clone Number:
ARC2565
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from HCT116 cells, using USP39 Rabbit mAb (CAB1393) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
