USP14 Rabbit Monoclonal Antibody (CAB19589)
- SKU:
- CAB19589
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- TGT
- Research Area:
- Immunology
Frequently bought together:
Description
Product Name: | USP14 Rabbit Monoclonal Antibody |
SKU: | CAB19589 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 371-473 of human USP14 (P54578). |
Sequence: | RSKF KDLE DKKV NQQP NTSD KKSS PQKE VKYE PFSF ADDI GSNN CGYY DLQA VLTH QGRS SSSG HYVS WVKR KQDE WIKF DDDK VSIV TPED ILRL SGGG DWH |
Tested Applications: | WB IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | TGT; Ubp6; USP14 |
Positive Sample: | HeLa,HCT 116,U-251MG,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | cell surface, cytoplasmic vesicle, cytosol, extracellular exosome, plasma membrane |
Calculated MW: | 56kDa |
Observed MW: | 60kDa |
This gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. Mice with a mutation that results in reduced expression of the ortholog of this protein are retarded for growth, develop severe tremors by 2 to 3 weeks of age followed by hindlimb paralysis and death by 6 to 10 weeks of age. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
Purification Method: | Affinity purification |
Gene ID: | 9097 |
Clone Number: | ARC2185 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |