The Anti-USP11 Antibody (CAB19562) is a valuable tool for researchers studying USP11, a key regulator of various cellular processes, including DNA damage repair and cell cycle progression. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting USP11 protein in human samples, making it suitable for use in Western blot applications. By binding to USP11, this antibody enables precise detection and analysis in a variety of cell types, providing valuable insights for studies in molecular biology and cancer research.USP11, a deubiquitinating enzyme, plays a crucial role in maintaining genomic stability and regulating cell proliferation.
Its dysregulation has been linked to cancer progression and other human diseases, highlighting its significance as a potential therapeutic target. By understanding the mechanisms by which USP11 influences cellular functions, researchers can uncover new strategies for developing targeted therapies for cancer and other diseases. The Anti-USP11 Antibody is a valuable tool for investigating the functions of USP11 and its potential implications in disease pathology.
Product Name:
USP11 Rabbit Monoclonal Antibody
SKU:
CAB19562
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 800-900 of human USP11 (P51784).
Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This gene encodes a deubiquitinating enzyme which lies in a gene cluster on chromosome Xp11.23
Purification Method:
Affinity purification
Gene ID:
8237
Clone Number:
ARC2176
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using USP11 Rabbit mAb (CAB19562) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
