The Anti-UFL1 Antibody (CAB20528) is a valuable tool for researchers studying UFL1, a key protein involved in cellular regulation and protein modification processes. This polyclonal antibody, produced in rabbits, specifically targets UFL1 and has been validated for use in Western blot applications, allowing for the detection and analysis of UFL1 levels in various biological samples.UFL1, a UFM1 ligase enzyme, plays a crucial role in the post-translational modification of proteins, particularly in the regulation of protein stability and function. Its involvement in cellular processes such as autophagy, protein degradation, and stress responses makes it a promising target for investigation in areas like cancer biology, neurodegenerative diseases, and metabolic disorders.
By using the Anti-UFL1 Antibody, researchers can gain insights into the function and regulation of UFL1, enabling a deeper understanding of its role in cellular physiology and disease development. This antibody offers high specificity and sensitivity, making it an indispensable tool for studies aiming to unravel the molecular mechanisms involving UFL1 in various pathological conditions.
Product Name:
UFL1 Rabbit Polyclonal Antibody
SKU:
CAB20528
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 601-794 of human UFL1 (NP_056138.1).
Enables UFM1 ligase activity and protein kinase binding activity. Involved in several processes, including cellular protein modification process; regulation of signal transduction; and reticulophagy. Acts upstream of or within several processes, including positive regulation of cell population proliferation; regulation of proteasomal ubiquitin-dependent protein catabolic process; and response to endoplasmic reticulum stress. Located in endoplasmic reticulum membrane; nucleus; and site of double-strand break. Part of protein-containing complex.
Purification Method:
Affinity purification
Gene ID:
23376
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from HepG2 cells, using UFL1 Rabbit pAb (CAB20528) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
