UCP1+UCP3 Rabbit Monoclonal Antibody (CAB19526)
- SKU:
- CAB19526
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- AI385626
- Slc25a7
- Ucp
Description
Product Name: | UCP1+UCP3 Rabbit Monoclonal Antibody |
SKU: | CAB19526 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-307 of mouse UCP1+UCP3 (P12242). |
Sequence: | MVNP TTSE VQPT MGVK IFSA GVSA CLAD IITF PLDT AKVR LQIQ GEGQ ASST IRYK GVLG TITT LAKT EGLP KLYS GLPA GIQR QISF ASLR IGLY DSVQ EYFS SGRE TPAS LGNK ISAG LMTG GVAV FIGQ PTEV VKVR MQAQ SHLH GIKP RYTG TYNA YRVI ATTE SLST LWKG TTPN LMRN VIIN CTEL VTYD LMKG ALVN NKIL ADDV PCHL LSAL VAGF CTTL LASP VDVV KTRF INSL PGQY PSVP SCAM SMYT KEGP TAFF KGFV ASFL RLGS WNVI MFVC FEQL KKEL MKSR QTVD CTT |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | AI385626; Slc25a7; Ucp; UCP1+UCP3 |
Positive Sample: | Mouse skeletal muscle,Mouse fat |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrial envelope, mitochondrial inner membrane, mitochondrion |
Calculated MW: | 34kDa |
Observed MW: | 30kDa |
Mitochondrial protein responsible for thermogenic respiration, a specialized capacity of brown adipose tissue and beige fat that participates in non-shivering adaptive thermogenesis to temperature and diet variations and more generally to the regulation of energy balance. Functions as a long-chain fatty acid/LCFA and proton symporter, simultaneously transporting one LCFA and one proton through the inner mitochondrial membrane. However, LCFAs remaining associated with the transporter via their hydrophobic tails, it results in an apparent transport of protons activated by LCFAs. Thereby, dissipates the mitochondrial proton gradient and converts the energy of substrate oxydation into heat instead of ATP. Regulates the production of reactive oxygen species/ROS by mitochondria.
Purification Method: | Affinity purification |
Gene ID: | 22227/22229 |
Clone Number: | ARC2304 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |