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UBE2B Rabbit Monoclonal Antibody (CAB0503)

SKU:
CAB0503
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
UBE2B
E2-17kDa
HHR6B
HR6B
RAD6B
UBC2
ubiquitin-conjugating enzyme E2 B
Research Area:
Epigenetics and Nuclear Signaling
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:UBE2B Rabbit Monoclonal Antibody
SKU:CAB0503
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse,Rat
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 53-152 of human UBE2B (P63146).
Sequence:FKLV IEFS EEYP NKPP TVRF LSKM FHPN VYAD GSIC LDIL QNRW SPTY DVSS ILTS IQSL LDEP NPNS PANS QAAQ LYQE NKRE YEKR VSAI VEQS WNDS
Tested Applications:WB IHC-P ELISA
Recommended Dilution:WB,1:500 - 1:1000 IHC-P,1:500 - 1:1000
Synonyms:HR6B; UBC2; HHR6B; RAD6B; E2-17kDa; UBE2B
Positive Sample:HeLa,293T,NIH/3T3,K-562,Mouse testis,Mouse heart,Rat testis
Conjugate:Unconjugated
Cellular Localization:Cell membrane, Nucleus.
Calculated MW:17kDa
Observed MW:17kDa

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution.

Purification Method:Affinity purification
Gene ID:7320
Clone Number:ARC2512
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of Rat testis, using UBE2B antibody (CAB0503) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

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