UBA3 Monoclonal Antibody (CAB20902)
- SKU:
- CAB20902
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Plant
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
Product Name: | UBA3 Monoclonal Antibody |
SKU: | CAB20902 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-463 of human UBA3 (NP_003959.3). |
Sequence: | MADG EEPE KKRR RIEE LLAE KMAV DGGC GDTG DWEG RWNH VKKF LERS GPFT HPDF EPST ESLQ FLLD TCKV LVIG AGGL GCEL LKNL ALSG FRQI HVID MDTI DVSN LNRQ FLFR PKDI GRPK AEVA AEFL NDRV PNCN VVPH FNKI QDFN DTFY RQFH IIVC GLDS IIAR RWIN GMLI SLLN YEDG VLDP SSIV PLID GGTE GFKG NARV ILPG MTAC IECT LELY PPQV NFPM CTIA SMPR LPEH CIEY VRML QWPK EQPF GEGV PLDG DDPE HIQW IFQK SLER ASQY NIRG VTYR LTQG VVKR IIPA VAST NAVI AAVC ATEV FKIA TSAY IPLN NYLV FNDV DGLY TYTF EAER KENC PACS QLPQ NIQF SPSA KLQE VLDY LTNS ASLQ MKSP AITA TLEG KNRT LYLQ SVTS IEER TRPN LSKT LKEL GLVD GQEL AVAD VTTP QTVL FKLH FTS |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:100 - 1:500 |
Synonyms: | NAE2; UBE1C; hUBA3; UBA3 |
Positive Sample: | Hep G2,K-562,RAW 264.7,Rat heart |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytosol, nucleus |
Calculated MW: | 52kDa |
Observed MW: | 52kDa |
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E1 ubiquitin-activating enzyme family. The encoded enzyme associates with AppBp1, an amyloid beta precursor protein binding protein, to form a heterodimer, and then the enzyme complex activates NEDD8, a ubiquitin-like protein, which regulates cell division, signaling and embryogenesis. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 9039 |
Clone Number: | ARC2865 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |