null

TUG Rabbit Monoclonal Antibody (CAB1396)

SKU:
CAB1396
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Synonyms:
ASPSCR1
ASPCR1
ASPL
ASPS
RCC17
TUG
UBXD9
UBXN9
tether containing UBX domain for GLUT4
Research Area:
Cell Biology
$167 - $503
Frequently bought together:

Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:TUG Rabbit Monoclonal Antibody
SKU:CAB1396
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human,Mouse
Immunogen:A synthetic peptide corresponding to a sequence within amino acids 200-300 of human TUG/ASPSCR1 (Q9BZE9).
Sequence:LPLE SGEL SRGD LSRP EDAD TSGP CCEH TQEK QSTR APAA APFV PFSG GGQR LGGP PGPT RPLT SSSA KLPK SLSS PGGP SKPK KSKS GQDP QQEQ EQER E
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:TUG; ASPL; ASPS; RCC17; UBXD9; UBXN9; ASPCR1; TUG/ASPSCR1
Positive Sample:293T, NIH/3T3, RD, Mouse testis
Conjugate:Unconjugated
Cellular Localization:Cytoplasm, Endomembrane system, Endoplasmic reticulum-Golgi intermediate compartment membrane, Nucleus, Peripheral membrane protein
Calculated MW:60kDa
Observed MW:75kDa

The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.

Purification Method:Affinity purification
Gene ID:79058
Clone Number:ARC2566
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts of various lysates, using TUG/ASPSCR1 antibody (CAB1396) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.

Related Products