TUG Rabbit Monoclonal Antibody (CAB1396)
- SKU:
- CAB1396
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- ASPSCR1
- ASPCR1
- ASPL
- ASPS
- RCC17
- TUG
- UBXD9
- UBXN9
- tether containing UBX domain for GLUT4
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TUG Rabbit Monoclonal Antibody |
SKU: | CAB1396 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 200-300 of human TUG/ASPSCR1 (Q9BZE9). |
Sequence: | LPLE SGEL SRGD LSRP EDAD TSGP CCEH TQEK QSTR APAA APFV PFSG GGQR LGGP PGPT RPLT SSSA KLPK SLSS PGGP SKPK KSKS GQDP QQEQ EQER E |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | TUG; ASPL; ASPS; RCC17; UBXD9; UBXN9; ASPCR1; TUG/ASPSCR1 |
Positive Sample: | 293T, NIH/3T3, RD, Mouse testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Endomembrane system, Endoplasmic reticulum-Golgi intermediate compartment membrane, Nucleus, Peripheral membrane protein |
Calculated MW: | 60kDa |
Observed MW: | 75kDa |
The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.
Purification Method: | Affinity purification |
Gene ID: | 79058 |
Clone Number: | ARC2566 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |