TTF1 Rabbit Monoclonal Antibody (CAB3292)
- SKU:
- CAB3292
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- BCH
- BHC
- NK-2
- NKX2.1
- NKX2A
- NMTC1
- T/EBP
- TEBP
- TITF1
- TTF-1
- TTF1
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TTF1 Rabbit Monoclonal Antibody |
SKU: | CAB3292 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1-100 of human NKX2-1 (P43699). |
Sequence: | MSMS PKHT TPFS VSDI LSPL EESY KKVG MEGG GLGA PLAA YRQG QAAP PTAA MQQH AVGH HGAV TAAY HMTA AGVP QLSH SAVG GYCN GNLG NMSE LPPY |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | BCH; BHC; NK-2; TEBP; TTF1; NKX2A; NMTC1; T/EBP; TITF1; TTF-1; NKX2.1; NKX2-1 |
Positive Sample: | HepG2,A-549,SH-SY5Y |
Conjugate: | Unconjugated |
Cellular Localization: | nucleoplasm, nucleus |
Calculated MW: | 39kDa |
Observed MW: | 42kDa |
This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea, choreoathetosis, congenital hypothyroidism, and neonatal respiratory distress, and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TTF1' with another gene, transcription termination factor 1, which plays a role in ribosomal gene transcription.
Purification Method: | Affinity purification |
Gene ID: | 7080 |
Clone Number: | ARC1942 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |