The TTC7A Polyclonal Antibody (CAB20595) is a valuable tool for researchers studying the TTC7A protein, a key component in the maintenance of intestinal homeostasis. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in Western blot applications. By specifically binding to the TTC7A protein, this antibody allows for the detection and analysis of TTC7A in a variety of cell types, making it ideal for investigations in the fields of gastrointestinal health and inflammatory bowel disease research.
TTC7A plays a crucial role in intestinal epithelial cell function, regulating processes such as cell growth, survival, and barrier integrity. Dysregulation of TTC7A has been linked to various gastrointestinal disorders, making it a promising target for therapeutic interventions. By further exploring the functions of TTC7A, researchers can gain valuable insights into the mechanisms underlying intestinal diseases and potentially develop novel treatment strategies to promote gut health and alleviate related conditions.
Product Name:
TTC7A Rabbit Polyclonal Antibody
SKU:
CAB20595
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human TTC7A (NP_001275880.1).
This gene encodes a protein containing tetratricopeptide repeats. Mutations in this gene disrupt intestinal development and can cause early onset inflammatory bowel disease and intestinal atresia. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
57217
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TTC7A antibody (CAB20595) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
