The TRMT2A/HTF9C Polyclonal Antibody (CAB0136) is a valuable tool for researchers studying TRMT2A, a protein involved in various cellular processes, including tRNA methylation and gene regulation. This antibody, raised in rabbits, exhibits high reactivity towards human samples and is validated for use in Western blot applications.TRMT2A, also known as HTF9C, plays a crucial role in modulating gene expression and protein synthesis by regulating tRNA modifications. Dysregulation of TRMT2A has been implicated in various diseases, including cancer and developmental disorders, making it a promising target for therapeutic interventions.
By using the TRMT2A/HTF9C Polyclonal Antibody, researchers can detect and analyze TRMT2A expression in different cell types, aiding in understanding its role in cellular functions and disease pathogenesis. This antibody is an essential tool for studies in molecular biology, cancer research, and therapeutic development targeting TRMT2A.
Product Name:
HTF9C Rabbit Monoclonal Antibody
SKU:
CAB0136
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TRMT2A/HTF9C (Q8IZ69).
The protein encoded by this gene is of unknown function. However, it is orthologous to the mouse Trmt2a gene and contains an RNA methyltransferase domain. Expression of this gene varies during the cell cycle, with aberrant expression being a possible biomarker in certain breast cancers. Several transcript variants encoding two different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
27037
Clone Number:
ARC2498
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of K-562, using TRMT2A/HTF9C Rabbit mAb (CAB0136) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
