The Anti-TRK Fused Gene (TFG) Antibody (CAB1534) is a valuable tool for researchers studying the TRK fused gene, a gene fusion associated with various types of cancers. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. It specifically targets the TFG protein, allowing for the detection and analysis of this important biomarker in a variety of cell types.The TFG gene fusion has been implicated in the development and progression of cancer, making it a promising target for therapeutic interventions.
By studying the role of TFG in cancer biology, researchers can gain valuable insights into the mechanisms underlying tumorigenesis and potentially identify new treatment strategies. The Anti-TRK Fused Gene Antibody offers a reliable tool for investigating the expression and function of TFG in cancer cells, making it an essential reagent for studies in oncology and molecular biology.
Product Name:
TRK fused gene (TFG) Rabbit Monoclonal Antibody
SKU:
CAB1534
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 301-400 of human TRK fused gene (TFG) (Q92734).
cytoplasm, cytosol, endoplasmic reticulum exit site
Calculated MW:
43kDa
Observed MW:
55kDa
There are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma, and may play a role in the NF-kappaB pathway. Multiple transcript variants have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10342
Clone Number:
ARC1882
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of Jurkat cells, using TRK fused gene (TFG) (TFG) Rabbit mAb (CAB1534) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
