The Trim33 Polyclonal Antibody (CAB20811) is a valuable tool for researchers studying Trim33, a protein involved in various cellular processes, including gene regulation and cell differentiation. This antibody, produced in rabbits, exhibits high specificity towards human samples and has been validated for use in Western blot applications. By binding to the Trim33 protein, this antibody enables the detection and analysis of Trim33 in a range of cell types, making it suitable for investigations in the fields of molecular biology and cancer research.Trim33, also known as Tif1 gamma, is a crucial component of the transcriptional regulatory network and is implicated in the development and progression of several diseases, including cancer.
Understanding the function and regulation of Trim33 can provide valuable insights into its role in cellular physiology and pathogenesis, paving the way for the development of targeted therapies for Trim33-related disorders. With its high specificity and sensitivity, the Trim33 Polyclonal Antibody is a reliable tool for researchers seeking to delve deeper into the mechanisms involving Trim33.
Product Name:
TRIM33 Polyclonal Antibody
SKU:
CAB20811
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 950-1090 of human TRIM33 (NP_056990.3).
The protein encoded by this gene is thought to be a transcriptional corepressor. However, molecules that interact with this protein have not yet been identified. The protein is a member of the tripartite motif family. This motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. Three alternatively spliced transcript variants for this gene have been described, however, the full-length nature of one variant has not been determined.
Purification Method:
Affinity purification
Gene ID:
51592
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TRIM33 antibody (CAB20811) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
