TRIM24 Monoclonal Antibody (CAB20938)
- SKU:
- CAB20938
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
Frequently bought together:
Description
| Product Name: | TRIM24 Monoclonal Antibody |
| SKU: | CAB20938 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human,Mouse,Rat |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 400-500 of human TRIM24 (O15164). |
| Sequence: | TNNT IQFH CDPS FWAQ NIIN LGSL VIED KESQ PQMP KQNP VVEQ NSQP PSGL SSNQ LSKF PTQI SLAQ LRLQ HMQQ QVMA QRQQ VQRR PAPV GLPN PRMQ G |
| Tested Applications: | WB ELISA |
| Recommended Dilution: | WB,1:500 - 1:1000 |
| Synonyms: | PTC6; TF1A; TIF1; RNF82; TIF1A; hTIF1; TIF1ALPHA; TRIM24 |
| Positive Sample: | HepG2,Mouse testis,Rat testis |
| Conjugate: | Unconjugated |
| Cellular Localization: | Cytoplasm, Nucleus. |
| Calculated MW: | 117kDa |
| Observed MW: | 117kDa/140kDa |
The protein encoded by this gene mediates transcriptional control by interaction with the activation function 2 (AF2) region of several nuclear receptors, including the estrogen, retinoic acid, and vitamin D3 receptors. The protein localizes to nuclear bodies and is thought to associate with chromatin and heterochromatin-associated factors. The protein is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains - a RING, a B-box type 1 and a B-box type 2 - and a coiled-coil region. Two alternatively spliced transcript variants encoding different isoforms have been described for this gene.
| Purification Method: | Affinity purification |
| Gene ID: | 8805 |
| Clone Number: | ARC2920 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |
 | Western blot analysis of extracts of various cell lines, using TRIM24 antibody (CAB20938) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s. |
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