The Anti-TREM2 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0213) is a cutting-edge tool for researchers studying TREM2, a key player in the immune response and neuroinflammation. This antibody is specifically engineered to target TREM2, a transmembrane receptor that regulates immune responses and phagocytosis in the central nervous system.By utilizing this antibody in experiments such as Western blotting and immunohistochemistry, researchers can accurately detect and analyze TREM2 expression in various cell types and tissues. This antibody is highly reactive with human samples and has been rigorously validated for its specificity and sensitivity in detecting TREM2 protein levels.
TREM2 has been linked to a variety of neurological disorders, including Alzheimer's disease and other neurodegenerative conditions. Research into TREM2 function is essential for understanding the underlying mechanisms of these diseases and developing potential therapeutic interventions.The Anti-TREM2 Chimeric Recombinant Rabbit Monoclonal Antibody (HDAB0213) is a valuable tool for scientists studying immunology, neuroinflammation, and neurodegenerative diseases. Its high specificity and sensitivity make it a reliable choice for researchers looking to advance our understanding of TREM2 and its role in immune regulation and neuroprotection.
SKU:
HDAB0213
Size:
100 µg
Clonality:
Monoclonal
Clone:
DMC223
Synonyms:
PLOSL2; TREM-2; Trem2a; Trem2b; Trem2c
Applications:
ELISA, Flow Cyt
Recommended Dilution:
ELISA 1:5000-10000; Flow Cyt 1:100
Host Species:
Rabbit
Isotype:
Rabbit/Human Fc chimeric IgG1
Reactivity:
Human
Purification Method:
Purified from cell culture supernatant by affinity chromatography
Formulation:
Powder
Buffer:
1XPBS
Storage:
Store at -20°C to -80°C for 12 months in lyophilized form. After reconstitution, if not intended for use within a month, aliquot and store at -80°C (Avoid repeated freezing and thawing).Lyophilized antibodies are shipped at ambient temperature.
Usage:
Research use only
Background:
This gene encodes a membrane protein that forms a receptor signaling complex with the TYRO protein tyrosine kinase binding protein. The encoded protein functions in immune response and may be involved in chronic inflammation by triggering the production of constitutive inflammatory cytokines. Defects in this gene are a cause of polycystic lipomembranous osteodysplasia with sclerosing leukoencephalopathy (PLOSL). Alternative splicing results in multiple transcript variants encoding different isoforms.
