The Anti-Trefoil Factor 3 Antibody (CAB4592) is a valuable tool for researchers studying Trefoil Factor 3, a protein involved in mucosal protection and repair. This antibody, generated in rabbits, has high specificity for human samples and has been validated for use in various applications, including Western blotting.Trefoil Factor 3, also known as TFF3, is known for its role in promoting mucosal healing and protecting the gastrointestinal tract from damage. Its expression is often dysregulated in various diseases, making it a potential therapeutic target for conditions such as inflammatory bowel disease and gastric cancer.
By using the Anti-Trefoil Factor 3 Antibody, researchers can detect and analyze TFF3 expression in different cell types, providing valuable insights into its function and potential implications in disease pathology. This antibody is a valuable tool for studies in gastrointestinal health, mucosal biology, and cancer research.
Product Name:
Trefoil Factor 3 Rabbit Monoclonal Antibody
SKU:
CAB4592
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-80 of human TFF3 (Q07654).
Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer and affect healing of the epithelium. This gene is expressed in goblet cells of the intestines and colon. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.
Purification Method:
Affinity purification
Gene ID:
7033
Clone Number:
ARC2664
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of TFF3 in paraffin-embedded human appendix using TFF3 Rabbit mAb (CAB4592) at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
