The TRAF6BP/TAX1BP1 Antibody (CAB19587) is a valuable tool for researchers studying the TRAF6BP/TAX1BP1 protein, a key player in immune signaling pathways. This polyclonal antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blotting applications.TRAF6BP/TAX1BP1 is involved in multiple cellular processes, including the regulation of NF-kB signaling, autophagy, and inflammation. Dysregulation of TRAF6BP/TAX1BP1 has been implicated in various diseases, such as cancer, autoimmune disorders, and inflammatory conditions.
By targeting this protein, researchers can gain insight into the molecular mechanisms underlying these diseases and potentially identify new therapeutic targets.This antibody enables the detection and analysis of TRAF6BP/TAX1BP1 in various cell types, making it an essential tool for studies in immunology, cancer research, and beyond. Understanding the role of TRAF6BP/TAX1BP1 in immune regulation is essential for advancing our knowledge of disease pathogenesis and developing targeted therapies. Order now to enhance your research with this high-quality antibody.
Product Name:
TRAF6BP/TAX1BP1 Rabbit Monoclonal Antibody
SKU:
CAB19587
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 690-789 of human TRAF6BP/TAX1BP1 (Q86VP1).
This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8887
Clone Number:
ARC2184
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TRAF6BP/TAX1BP1 Rabbit mAb (CAB19587) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
