TRAF6BP/TAX1BP1 Rabbit Monoclonal Antibody (CAB19587)
- SKU:
- CAB19587
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CALCOCO3
- T6BP
- TXBP151
- Research Area:
- Cell Biology
Frequently bought together:
Description
| Product Name: | TRAF6BP/TAX1BP1 Rabbit Monoclonal Antibody |
| SKU: | CAB19587 |
| Size: | 20uL, 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human,Mouse |
| Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 690-789 of human TRAF6BP/TAX1BP1 (Q86VP1). |
| Sequence: | DSED SKED ENVP TAPD PPSQ HLRG HGTG FCFD SSFD VHKK CPLC ELMF PPNY DQSK FEEH VESH WKVC PMCS EQFP PDYD QQVF ERHV QTHF DQNV LNFD |
| Tested Applications: | WB ELISA |
| Recommended Dilution: | WB,1:500 - 1:2000 |
| Synonyms: | T6BP; TXBP151; CALCOCO3; TRAF6BP/TAX1BP1 |
| Positive Sample: | A549,U-937,U-251MG,Mouse testis |
| Conjugate: | Unconjugated |
| Cellular Localization: | Cytosol, Extracellular exosome |
| Calculated MW: | 91kDa |
| Observed MW: | 100kDa |
This gene encodes a HTLV-1 tax1 binding protein. The encoded protein interacts with TNFAIP3, and inhibits TNF-induced apoptosis by mediating the TNFAIP3 anti-apoptotic activity. Degradation of this protein by caspase-3-like family proteins is associated with apoptosis induced by TNF. This protein may also have a role in the inhibition of inflammatory signaling pathways. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Purification Method: | Affinity purification |
| Gene ID: | 8887 |
| Clone Number: | ARC2184 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |
 | Western blot analysis of extracts of various cell lines, using TRAF6BP/TAX1BP1 Rabbit mAb (CAB19587) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s. |
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