The TNKS1BP1 Polyclonal Antibody (CAB20388) is a valuable tool for researchers studying TNKS1BP1, a crucial protein involved in telomere maintenance and DNA repair processes. This antibody, produced in rabbits, demonstrates high specificity and sensitivity in detecting TNKS1BP1 in human samples, making it an ideal choice for applications such as Western blotting.TNKS1BP1 is known to interact with tankyrase enzymes and plays a key role in regulating telomere length and DNA damage response pathways. Dysregulation of TNKS1BP1 has been linked to various diseases, including cancer and genetic disorders.
Therefore, investigating the function and expression of TNKS1BP1 is essential for understanding its role in disease development and progression.By using the TNKS1BP1 Polyclonal Antibody, researchers can further explore the mechanisms by which TNKS1BP1 influences cellular processes and potentially identify novel therapeutic targets for diseases associated with its dysfunction. This antibody offers a reliable tool for studying TNKS1BP1 in various experimental settings, contributing to advancements in the fields of cancer biology and genomic stability.
Product Name:
TNKS1BP1 Rabbit Polyclonal Antibody
SKU:
CAB20388
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 700-1000 of human TNKS1BP1 (NP_203754.2).
Enables ankyrin repeat binding activity and enzyme binding activity. Involved in cellular response to ionizing radiation; double-strand break repair; and positive regulation of protein phosphorylation. Located in several cellular components, including actin cytoskeleton; adherens junction; and heterochromatin. Part of CCR4-NOT complex.
Purification Method:
Affinity purification
Gene ID:
85456
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human colon using TNKS1BP1 Rabbit pAb (CAB20388) at dilution of 1:200 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
