TIN2/TINF2 Rabbit Monoclonal Antibody (CAB9750)
- SKU:
- CAB9750
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- DKCA3
- TIN2
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TIN2/TINF2 Rabbit Monoclonal Antibody |
SKU: | CAB9750 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 210-309 of human TIN2/TINF2 (Q9BSI4). |
Sequence: | NLAE PMEQ NPPQ QQRL ALHN PLPK AKPG THLP QGPS SRTH PEPL AGRH FNLA PLGR RRVQ SQWA STRG GHKE RPTV MLFP FRNL GSPT QVIS KPES KEEH |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | TIN2; DKCA3; TIN2/TINF2 |
Positive Sample: | Hep G2,A549,Mouse testis,Mouse thymus,Rat lung,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus, Nucleus matrix, telomere. |
Calculated MW: | 50kDa |
Observed MW: | 45kDa |
This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome.
Purification Method: | Affinity purification |
Gene ID: | 26277 |
Clone Number: | ARC1732 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |