TIMP2 Monoclonal Antibody (CAB20766)
- SKU:
- CAB20766
- Product Type:
- Antibody
- Antibody Type:
- Secondary Antibody
- Host Species:
- Goat
- Isotype:
- Fluorescein conjugated IgG
Frequently bought together:
Description
Product Name: | TIMP2 Monoclonal Antibody |
SKU: | CAB20766 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat,African green monkey |
Immunogen: | Recombinant protein of human TIMP2. |
Sequence: | VSLD VGGK KEYL IAGK AEGD GKMH ITLC DFIV PWDT LSTT QKKS LNHR YQMG CECK ITRC PMIP CYIS SPDE CLWM DWVT EKNI NGHQ AKFF ACIK RSDG S |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | DDC8; CSC-21K; TIMP2 |
Positive Sample: | SH-SY5Y,HT-1080,Rat brain,COS-7,Mouse testis,Mouse brain,Mouse lung |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 24kDa |
Observed MW: | 22kDa |
This gene is a member of the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix. In addition to an inhibitory role against metalloproteinases, the encoded protein has a unique role among TIMP family members in its ability to directly suppress the proliferation of endothelial cells. As a result, the encoded protein may be critical to the maintenance of tissue homeostasis by suppressing the proliferation of quiescent tissues in response to angiogenic factors, and by inhibiting protease activity in tissues undergoing remodelling of the extracellular matrix.
Purification Method: | Affinity purification |
Gene ID: | 7077 |
Clone Number: | ARC51187 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3. |