Timeless Rabbit Monoclonal Antibody (CAB0512)
- SKU:
- CAB0512
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- TIM
- TIM1
- hTIM
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Timeless Rabbit Monoclonal Antibody |
SKU: | CAB0512 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1058-1208 of human Timeless (Q9UNS1). |
Sequence: | EQFQ QLLR KLGV RPPA SGQE TFWR IPAK LSPT QLRR AAAS LSQP EEEQ KLQP ELQP KVPG EQGS DEEH CKEH RAQA LRAL LLAH KKKA GLAS PEEE DAVG KEPL KAAP KKRQ LLDS DEEQ EEDE GRNR APEL GAPG IQKK KRYQ IEDD EDD |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 |
Synonyms: | TIM; TIM1; hTIM; FASPS4; Timeless |
Positive Sample: | 293T,Hep G2,A-549 |
Conjugate: | Unconjugated |
Cellular Localization: | nucleoplasm, nucleus |
Calculated MW: | 139kDa |
Observed MW: | 150kDa |
The protein encoded by this gene is highly conserved and is involved in cell survival after damage or stress, increase in DNA polymerase epsilon activity, maintenance of telomere length, and epithelial cell morphogenesis. The encoded protein also plays a role in the circadian rhythm autoregulatory loop, interacting with the PERIOD genes (PER1, PER2, and PER3) and others to downregulate activation of PER1 by CLOCK/ARNTL. Changes in this gene or its expression may promote prostate cancer, lung cancer, breast cancer, and mental disorders.
Purification Method: | Affinity purification |
Gene ID: | 8914 |
Clone Number: | ARC1827 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |