The Anti-TIGIT Antibody (CAB20350) offered by Assay Genie is a valuable tool for researchers studying the TIGIT protein, a cell surface molecule involved in immune regulation. This polyclonal antibody, generated in rabbits, is highly specific for human samples and is validated for use in Western blot applications.TIGIT, also known as T cell immunoreceptor with Ig and ITIM domains, plays a crucial role in immune responses by inhibiting T cell activation and promoting immune tolerance. Understanding the function of TIGIT is essential for research in immunology and cancer, as it is implicated in the regulation of immune checkpoints and the suppression of anti-tumor immune responses.
The Anti-TIGIT Antibody enables precise detection and analysis of TIGIT protein expression in various cell types, making it ideal for investigating the role of TIGIT in diseases such as cancer and autoimmune disorders. By targeting TIGIT, researchers can develop innovative therapies that modulate immune responses and enhance the efficacy of cancer immunotherapy. Discover the potential of TIGIT in immune regulation with the Anti-TIGIT Antibody from Assay Genie.
Product Name:
TIGIT Rabbit Polyclonal Antibody
SKU:
CAB20350
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 167-244 of human TIGIT (NP_776160.2).
This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.
Purification Method:
Affinity purification
Gene ID:
201633
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TIGIT antibody (CAB20350) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
