The Anti-Thyroid Peroxidase Antibody (CAB19547) is a crucial tool designed for research involving thyroid peroxidase, an enzyme involved in thyroid hormone synthesis. This polyclonal antibody, raised in rabbits, is highly specific and reactive to human samples, making it ideal for various immunological studies.Thyroid peroxidase is essential for thyroid hormone production and is a key target in autoimmune thyroid diseases such as Hashimoto's thyroiditis and Graves' disease. The Anti-Thyroid Peroxidase Antibody (CAB19547) enables the detection and analysis of thyroid peroxidase levels, allowing researchers to study its role in thyroid function and dysfunction.
By understanding the activity of thyroid peroxidase and its association with autoimmune thyroid diseases, researchers can develop new insights and potential therapeutic targets for the management of these conditions. The Anti-Thyroid Peroxidase Antibody (CAB19547) holds great promise in advancing research in thyroid disorders and improving diagnostic and treatment strategies.
Product Name:
Thyroid Peroxidase Rabbit Monoclonal Antibody
SKU:
CAB19547
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human Thyroid Peroxidase (P07202).
This gene encodes a membrane-bound glycoprotein. The encoded protein acts as an enzyme and plays a central role in thyroid gland function. The protein functions in the iodination of tyrosine residues in thyroglobulin and phenoxy-ester formation between pairs of iodinated tyrosines to generate the thyroid hormones, thyroxine and triiodothyronine. Mutations in this gene are associated with several disorders of thyroid hormonogenesis, including congenital hypothyroidism, congenital goiter, and thyroid hormone organification defect IIA. Multiple transcript variants encoding distinct isoforms have been identified for this gene, but the full-length nature of some variants has not been determined.
Purification Method:
Affinity purification
Gene ID:
7173
Clone Number:
ARC2170
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of paraffin-embedded human thyroid cancer using Thyroid Peroxidase Rabbit mAb (CAB19547) at dilution of 1:100 (40x lens).Perform microwave antigen retrieval with 10 mM Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
