Thyroglobulin Rabbit Monoclonal Antibody (CAB3407)
- SKU:
- CAB3407
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- AITD3
- TGN
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | Thyroglobulin Rabbit Monoclonal Antibody |
SKU: | CAB3407 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 1000-1100 of human Thyroglobulin (P01266). |
Sequence: | STLS FYQR RRFS PDDS AGAS ALLR SGPY MPQC DAFG SWEP VQCH AGTG HCWC VDEK GGFI PGSL TARS LQIP QCPT TCEK SRTS GLLS SWKQ ARSQ ENPS P |
Tested Applications: | IHC-P IF/ICC ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | TGN; AITD3; Thyroglobulin |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 305kDa |
Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.
Purification Method: | Affinity purification |
Gene ID: | 7038 |
Clone Number: | ARC1971 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |