The Thyroglobulin Polyclonal Antibody (CAB3407) is a valuable tool for researchers studying thyroglobulin, a protein produced by the thyroid gland involved in the synthesis of thyroid hormones. This antibody, raised in rabbits, specifically targets thyroglobulin in human samples and is validated for use in various applications, including Western blotting and immunohistochemistry.Thyroglobulin is a key player in thyroid function and can serve as a biomarker for thyroid disorders, including thyroid cancer.
By using the Thyroglobulin Polyclonal Antibody, researchers can accurately detect and analyze thyroglobulin levels in different cell types, aiding in the investigation of thyroid diseases and potential therapeutic targets.With its high reactivity and specificity, the Thyroglobulin Polyclonal Antibody is a reliable tool for researchers in the fields of endocrinology, oncology, and immunology looking to deepen their understanding of thyroid function and related disorders.
Product Name:
Thyroglobulin Rabbit Monoclonal Antibody
SKU:
CAB3407
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1000-1100 of human Thyroglobulin (P01266).
Thyroglobulin (Tg) is a glycoprotein homodimer produced predominantly by the thryroid gland. It acts as a substrate for the synthesis of thyroxine and triiodothyronine as well as the storage of the inactive forms of thyroid hormone and iodine. Thyroglobulin is secreted from the endoplasmic reticulum to its site of iodination, and subsequent thyroxine biosynthesis, in the follicular lumen. Mutations in this gene cause thyroid dyshormonogenesis, manifested as goiter, and are associated with moderate to severe congenital hypothyroidism. Polymorphisms in this gene are associated with susceptibility to autoimmune thyroid diseases (AITD) such as Graves disease and Hashimoto thryoiditis.
Purification Method:
Affinity purification
Gene ID:
7038
Clone Number:
ARC1971
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Immunohistochemistry analysis of Thyroglobulin in paraffin-embedded human thyroid cancer using Thyroglobulin Rabbit mAb (CAB3407) at dilution of 1:100 (40x lens).Perform high pressure antigen retrieval with 10 mM citrate buffer pH 6.0 before commencing with IHC staining protocol.
