The TGN46/ Tgoln2 polyclonal antibody (CAB19618) is a highly specific research tool designed for the detection and analysis of the TGN46/ Tgoln2 protein. This antibody, raised in rabbits, is validated for use in various applications, including Western blotting and immunofluorescence, making it an ideal choice for studies in cell biology and intracellular trafficking.TGN46/ Tgoln2 is a trans-Golgi network protein involved in protein trafficking and sorting within the cell. It plays a crucial role in the maintenance of organelle structure and function, making it a key target for research into cellular processes and disease mechanisms.
By utilizing the TGN46/ Tgoln2 antibody, researchers can gain valuable insights into the localization and function of this protein in different cell types and experimental conditions. This antibody provides a reliable tool for studying intracellular transport pathways and elucidating the role of TGN46/ Tgoln2 in various cellular processes, offering new opportunities for understanding cell biology and disease pathology.
Product Name:
TGN46/TGOLN2 Rabbit Monoclonal Antibody
SKU:
CAB19618
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human TGN46/TGOLN2 (O43493).
endoplasmic reticulum lumen, endosome, Golgi apparatus, nucleoplasm, plasma membrane, trans-Golgi network, trans-Golgi network transport vesicle, transport vesicle
Calculated MW:
46kDa
Observed MW:
90-100kDa
This gene encodes a type I integral membrane protein that is localized to the trans-Golgi network, a major sorting station for secretory and membrane proteins. The encoded protein cycles between early endosomes and the trans-Golgi network, and may play a role in exocytic vesicle formation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
10618
Clone Number:
ARC2197
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using TGN46/TGOLN2 Rabbit mAb (CAB19618) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
